Gene Protein Name UniProt Location Drugs Mutations
KDR Vascular endothelial growth factor receptor 2 P35968 Cell junction 9 — View →
KIT Mast/stem cell growth factor receptor Kit P10721 Cell membrane 9 28 View →
NR1I2 Nuclear receptor subfamily 1 group I member 2 O75469 Nucleus 9 — View →
TOP2A DNA topoisomerase 2-alpha P11388 Cytoplasm 9 — View →
EGFR Epidermal growth factor receptor P00533 Cell membrane 8 12 View →
ESR1 Estrogen receptor P03372 Nucleus 8 — View →
AR Androgen receptor P10275 Nucleus 7 22 View →
FCGR1A High affinity immunoglobulin gamma Fc receptor I P12314 Cell membrane 7 — View →
GNRHR Gonadotropin-releasing hormone receptor P30968 Cell membrane 7 — View →
ABL1 Tyrosine-protein kinase ABL1 P00519 Cytoplasm 6 63 View →
C1QA Complement C1q subcomponent subunit A P02745 Secreted 6 — View →
C1QB Complement C1q subcomponent subunit B P02746 Secreted 6 — View →
C1QC Complement C1q subcomponent subunit C P02747 Secreted 6 — View →
C1R Complement C1r subcomponent P00736 Cytoplasmic 6 — View →
FCGR2A Low affinity immunoglobulin gamma Fc region receptor II-a P12318 Cell membrane 6 — View →
FCGR2B Low affinity immunoglobulin gamma Fc region receptor II-b P31994 Cell membrane 6 — View →
FCGR2C Low affinity immunoglobulin gamma Fc region receptor II-c P31995 Cytoplasm 6 — View →
FCGR3A Low affinity immunoglobulin gamma Fc region receptor III-A P08637 Cell membrane 6 — View →
FCGR3B Low affinity immunoglobulin gamma Fc region receptor III-B O75015 Cell membrane 6 — View →
FLT1 Vascular endothelial growth factor receptor 1 P17948 Cell membrane 6 — View →
FLT4 Vascular endothelial growth factor receptor 3 P35916 Cell membrane 6 — View →
PDGFRB Platelet-derived growth factor receptor beta P09619 Cell membrane 6 — View →
TYMS Thymidylate synthase P04818 Nucleus 6 — View →
ERBB2 Receptor tyrosine-protein kinase erbB-2 P04626 Cell membrane 5 4 View →
HDAC1 Histone deacetylase 1 Q13547 Nucleus 5 — View →
PDGFRA Platelet-derived growth factor receptor alpha P16234 Cell membrane 5 3 View →
RRM1 Ribonucleoside-diphosphate reductase large subunit P23921 Cytoplasm 5 — View →
SHBG Sex hormone-binding globulin P04278 Secreted 5 — View →
TUBB1 Tubulin beta-1 chain Q9H4B7 Cytoplasm 5 — View →
BRAF Serine/threonine-protein kinase B-raf P15056 Nucleus 4 5 View →
C1S Complement C1s subcomponent P09871 Cytoplasmic 4 — View →
CYP19A1 Aromatase P11511 Membrane 4 — View →
FGFR1 Fibroblast growth factor receptor 1 P11362 Cell membrane 4 — View →
POLA1 DNA polymerase alpha catalytic subunit P09884 Nucleus 4 — View →
RET Proto-oncogene tyrosine-protein kinase receptor Ret P07949 Cell membrane 4 — View →
BCL2 Apoptosis regulator Bcl-2 P10415 Mitochondrion outer membrane 3 — View →
BCR Breakpoint cluster region protein P11274 Cell junction 3 — View →
CSF3R Granulocyte colony-stimulating factor receptor Q99062 Secreted 3 — View →
DHFR Dihydrofolate reductase P00374 — 3 — View →
ESR2 Estrogen receptor beta Q92731 Nucleus 3 — View →
FGFR2 Fibroblast growth factor receptor 2 P21802 Cell membrane 3 — View →
FGFR3 Fibroblast growth factor receptor 3 P22607 Cell membrane 3 — View →
FLT3 Receptor-type tyrosine-protein kinase FLT3 P36888 Membrane 3 5 View →
IFNAR1 Interferon alpha/beta receptor 1 P17181 Membrane 3 — View →
IFNAR2 Interferon alpha/beta receptor 2 P48551 Membrane 3 — View →
LYN Tyrosine-protein kinase Lyn P07948 Cell membrane 3 — View →
MAP2 Microtubule-associated protein 2 P11137 Cytoplasm 3 — View →
MS4A1 B-lymphocyte antigen CD20 P11836 Cell membrane 3 — View →
PGR Progesterone receptor P06401 Nucleus 3 — View →
RAF1 RAF proto-oncogene serine/threonine-protein kinase P04049 Cytoplasm 3 — View →
RXRA Retinoic acid receptor RXR-alpha P19793 Nucleus 3 — View →
RXRB Retinoic acid receptor RXR-beta P28702 Nucleus 3 — View →
RXRG Retinoic acid receptor RXR-gamma P48443 Nucleus 3 — View →
SRC Proto-oncogene tyrosine-protein kinase Src P12931 Cell membrane 3 — View →
TUBB Tubulin beta chain P07437 Cytoplasm 3 — View →
ALK ALK tyrosine kinase receptor Q9UM73 Cell membrane 2 49 View →
BTK Tyrosine-protein kinase BTK Q06187 Cytoplasm 2 11 View →
CRBN Protein cereblon Q96SW2 Cytoplasm 2 — View →
CSF1R Macrophage colony-stimulating factor 1 receptor P07333 Cell membrane 2 — View →
CYP26C1 Cytochrome P450 26C1 Q6V0L0 Membrane 2 — View →
DNMT1 DNA (cytosine-5)-methyltransferase 1 P26358 Nucleus 2 — View →
ELANE Neutrophil elastase P08246 Cytoplasmic 2 — View →
EPHA2 Ephrin type-A receptor 2 P29317 Cell membrane 2 — View →
ESRRG Estrogen-related receptor gamma P62508 Nucleus 2 — View →
FGFR4 Fibroblast growth factor receptor 4 P22455 Cell membrane 2 — View →
FRK Tyrosine-protein kinase FRK P42685 Cytoplasm 2 — View →
HDAC2 Histone deacetylase 2 Q92769 Nucleus 2 — View →
HDAC6 Histone deacetylase 6 Q9UBN7 Nucleus 2 — View →
IL2RA Interleukin-2 receptor subunit alpha P01589 Membrane 2 — View →
IL2RB Interleukin-2 receptor subunit beta P14784 Membrane 2 — View →
IL2RG Cytokine receptor common subunit gamma P31785 Membrane 2 — View →
JUN Transcription factor AP-1 P05412 Nucleus 2 — View →
KCNH2 Potassium voltage-gated channel subfamily H member 2 Q12809 Cell membrane 2 — View →
LCK Tyrosine-protein kinase Lck P06239 Cytoplasm 2 — View →
LHCGR Lutropin-choriogonadotropic hormone receptor P22888 Cell membrane 2 — View →
MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Q02750 Cytoplasm 2 — View →
MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 P36507 Cytoplasm 2 — View →
MAP4 Microtubule-associated protein 4 P27816 Cytoplasm 2 — View →
MAPT Microtubule-associated protein tau P10636 Cytoplasm 2 — View →
MET Hepatocyte growth factor receptor P08581 Membrane 2 10 View →
MTOR Serine/threonine-protein kinase mTOR P42345 Endoplasmic reticulum membrane 2 2 View →
NTRK1 High affinity nerve growth factor receptor P04629 Cell membrane 2 — View →
PDCD1 Programmed cell death protein 1 Q15116 Membrane 2 — View →
PPAT Amidophosphoribosyltransferase Q06203 — 2 — View →
PSMB1 Proteasome subunit beta type-1 P20618 Cytoplasm 2 — View →
PSMB5 Proteasome subunit beta type-5 P28074 Cytoplasm 2 — View →
PTGS2 Prostaglandin G/H synthase 2 P35354 Microsome membrane 2 — View →
RARA Retinoic acid receptor alpha P10276 Nucleus 2 — View →
RARB Retinoic acid receptor beta P10826 Nucleus 2 — View →
RARG Retinoic acid receptor gamma P13631 Nucleus 2 — View →
SMO Smoothened homolog Q99835 Membrane 2 10 View →
TEK Angiopoietin-1 receptor Q02763 Cell membrane 2 — View →
TOP1 DNA topoisomerase 1 P11387 Nucleus 2 — View →
TOP1MT DNA topoisomerase I, mitochondrial Q969P6 Mitochondrion 2 — View →
TOP2B DNA topoisomerase 2-beta Q02880 Cytoplasm 2 — View →
TUBA4A Tubulin alpha-4A chain P68366 Cytoplasm 2 — View →
VEGFA Vascular endothelial growth factor A P15692 Secreted 2 — View →
A2M Alpha-2-macroglobulin P01023 Secreted 1 — View →
ABCC1 Multidrug resistance-associated protein 1 P33527 Cell membrane 1 — View →
ABL2 Abelson tyrosine-protein kinase 2 P42684 Cytoplasm 1 — View →
ACPP Prostatic acid phosphatase P15309 Secreted 1 — View →
ADA Adenosine deaminase P00813 Cell membrane 1 — View →
AHR Aryl hydrocarbon receptor P35869 Cytoplasm 1 — View →
AKT1 RAC-alpha serine/threonine-protein kinase P31749 Cytoplasm 1 — View →
ALB Serum albumin P02768 Secreted 1 — View →
ALDH1A1 Retinal dehydrogenase 1 P00352 Cytoplasm 1 — View →
ALDH1A2 Retinal dehydrogenase 2 O94788 Cytoplasm 1 — View →
ALOX5 Arachidonate 5-lipoxygenase P09917 Cytoplasm 1 — View →
ATIC Bifunctional purine biosynthesis protein PURH P31939 Cytoplasmic 1 — View →
ATOX1 Copper transport protein ATOX1 O00244 — 1 — View →
BCR/ABL fusion BCR/ABL fusion protein isoform X9 A9UF02 — 1 — View →
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma Q13555 Sarcoplasmic reticulum membrane 1 — View →
CCND1 G1/S-specific cyclin-D1 P24385 Nucleus 1 — View →
CD19 B-lymphocyte antigen CD19 P15391 Membrane 1 — View →
CD33 Myeloid cell surface antigen CD33 P20138 Cell membrane 1 — View →
CD3D T-cell surface glycoprotein CD3 delta chain P04234 Membrane 1 — View →
CD52 CAMPATH-1 antigen P31358 Cell membrane 1 — View →
CDH5 Cadherin-5 P33151 Cell junction 1 — View →
CDK2 Cyclin-dependent kinase 2 P24941 Cytoplasm 1 — View →
CDK4 Cyclin-dependent kinase 4 P11802 Cytoplasm 1 — View →
CDK6 Cyclin-dependent kinase 6 Q00534 Cytoplasm 1 — View →
CDKN1A Cyclin-dependent kinase inhibitor 1 P38936 Cytoplasm 1 — View →
CHD1 Chromodomain-helicase-DNA-binding protein 1 O14646 Nucleus 1 — View →
CMPK1 UMP-CMP kinase P30085 Nucleus 1 — View →
CSF2RA Granulocyte-macrophage colony-stimulating factor receptor subunit alpha P15509 Cell membrane 1 — View →
CSF2RB Cytokine receptor common subunit beta P32927 Membrane 1 — View →
CSK Tyrosine-protein kinase CSK P41240 Cytoplasm 1 — View →
CTLA4 Cytotoxic T-lymphocyte protein 4 P16410 Cell membrane 1 — View →
CXCR4 C-X-C chemokine receptor type 4 P61073 Cell membrane 1 — View →
CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial P05108 Mitochondrion membrane 1 — View →
CYP11B1 Cytochrome P450 11B1, mitochondrial P15538 Mitochondrion membrane 1 — View →
CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase P05093 Membrane 1 — View →
CYP26A1 Cytochrome P450 26A1 O43174 Endoplasmic reticulum membrane 1 — View →
CYP26B1 Cytochrome P450 26B1 Q9NR63 Endoplasmic reticulum membrane 1 — View →
DCK Deoxycytidine kinase P27707 Nucleus 1 — View →
DDR1 Epithelial discoidin domain-containing receptor 1 Q08345 Cell membrane 1 — View →
DDR2 Discoidin domain-containing receptor 2 Q16832 Cell membrane 1 — View →
EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Q15125 Endoplasmic reticulum membrane 1 — View →
EPHA5 Ephrin type-A receptor 5 P54756 Cell membrane 1 — View →
EPHB4 Ephrin type-B receptor 4 P54760 Cell membrane 1 — View →
ERBB4 Receptor tyrosine-protein kinase erbB-4 Q15303 Cell membrane 1 — View →
ESRRA Steroid hormone receptor ERR1 P11474 Nucleus 1 — View →
ESRRB Steroid hormone receptor ERR2 O95718 Nucleus 1 — View →
FDX1 Adrenodoxin, mitochondrial P10109 Mitochondrion matrix 1 — View →
FGF1 Fibroblast growth factor 1 P05230 Secreted 1 — View →
FGR Tyrosine-protein kinase Fgr P09769 Cell membrane 1 — View →
FPGS Folylpolyglutamate synthase, mitochondrial Q05932 Mitochondrion inner membrane 1 — View →
FYN Tyrosine-protein kinase Fyn P06241 Cytoplasm 1 — View →
GART Trifunctional purine biosynthetic protein adenosine-3 P22102 — 1 — View →
GPRC5A Retinoic acid-induced protein 3 Q8NFJ5 Cell membrane 1 — View →
GSR Glutathione reductase, mitochondrial P00390 Mitochondrion 1 — View →
HCK Tyrosine-protein kinase HCK P08631 Lysosome 1 — View →
HDAC3 Histone deacetylase 3 O15379 Nucleus 1 — View →
HDAC4 Histone deacetylase 4 P56524 Nucleus 1 — View →
HDAC8 Histone deacetylase 8 Q9BY41 Nucleus 1 — View →
HPGDS Hematopoietic prostaglandin D synthase O60760 Cytoplasm 1 — View →
HPRT1 Hypoxanthine-guanine phosphoribosyltransferase P00492 Cytoplasm 1 — View →
HSPA8 Heat shock cognate 71 kDa protein P11142 Cytoplasm 1 — View →
IGFBP3 Insulin-like growth factor-binding protein 3 P17936 Secreted 1 — View →
IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta O14920 Cytoplasm 1 — View →
IL3RA Interleukin-3 receptor subunit alpha P26951 Membrane 1 — View →
IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 P20839 Cytoplasm 1 — View →
ITGA4 Integrin alpha-4 P13612 Membrane 1 — View →
ITGB7 Integrin beta-7 P26010 Membrane 1 — View →
ITK Tyrosine-protein kinase ITK/TSK Q08881 Cytoplasm 1 — View →
LCN1 Lipocalin-1 P31025 Secreted 1 — View →
LDLR Low-density lipoprotein receptor P01130 Cell membrane 1 — View →
LIG1 DNA ligase 1 P18858 Nucleus 1 — View →
LIG3 DNA ligase 3 P49916 Mitochondrion 1 — View →
LIMK1 LIM domain kinase 1 P53667 Cytoplasm 1 — View →
MAOA Amine oxidase [flavin-containing] A P21397 Mitochondrion outer membrane 1 — View →
MAP1A Microtubule-associated protein 1A P78559 Cytoplasm 1 — View →
MAP3K2 Mitogen-activated protein kinase kinase kinase 2 Q9Y2U5 Cytoplasm 1 — View →
MAPK1 Mitogen-activated protein kinase 1 P28482 Cytoplasm 1 — View →
MAPK11 Mitogen-activated protein kinase 11 Q15759 Cytoplasm 1 — View →
MAPK14 Mitogen-activated protein kinase 14 Q16539 Cytoplasm 1 — View →
MAPK3 Mitogen-activated protein kinase 3 P27361 Cytoplasm 1 — View →
MGEA5 Protein O-GlcNAcase O60502 Nucleus 1 — View →
MPG DNA-3-methyladenine glycosylase P29372 Cytoplasm 1 — View →
NCOA2 Nuclear receptor coactivator 2 Q15596 Nucleus 1 — View →
NEK11 Serine/threonine-protein kinase Nek11 Q8NG66 Nucleus 1 — View →
NOLC1 Nucleolar and coiled-body phosphoprotein 1 Q14978 Nucleus 1 — View →
NR0B1 Nuclear receptor subfamily 0 group B member 1 P51843 Nucleus 1 — View →
NR3C1 Glucocorticoid receptor P04150 Cytoplasm 1 — View →
NR4A3 Nuclear receptor subfamily 4 group A member 3 Q92570 Nucleus 1 — View →
OBP2A Odorant-binding protein 2a Q9NY56 Secreted 1 — View →
ORM1 Alpha-1-acid glycoprotein 1 P02763 Secreted 1 — View →
PARP1 Poly [ADP-ribose] polymerase 1 P09874 Nucleus 1 — View →
PARP2 Poly [ADP-ribose] polymerase 2 Q9UGN5 Nucleus 1 — View →
PARP3 Poly [ADP-ribose] polymerase 3 Q9Y6F1 Nucleus 1 — View →
PDK4 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial Q16654 Mitochondrion matrix 1 — View →
PGD 6-phosphogluconate dehydrogenase, decarboxylating P52209 Cytoplasm 1 — View →
PGF Placenta growth factor P49763 Secreted 1 — View →
PML Protein PML P29590 Nucleus 1 — View →
PNP Purine nucleoside phosphorylase P00491 Cytoplasm 1 — View →
POLA2 DNA polymerase alpha subunit B Q14181 Nucleus 1 — View →
POLB DNA polymerase beta P06746 Nucleus 1 — View →
POLE DNA polymerase epsilon catalytic subunit A Q07864 Nucleus 1 — View →
POLE2 DNA polymerase epsilon subunit 2 P56282 Nucleus 1 — View →
POLE3 DNA polymerase epsilon subunit 3 Q9NRF9 Nucleus 1 — View →
POLE4 DNA polymerase epsilon subunit 4 Q9NR33 Nucleus 1 — View →
PRG2 Bone marrow proteoglycan P13727 Secreted 1 — View →
PRKCA Protein kinase C alpha type P17252 Cytoplasm 1 — View →
PSG5 Pregnancy-specific beta-1-glycoprotein 5 Q15238 Secreted 1 — View →
PSMB10 Proteasome subunit beta type-10 P40306 Cytoplasm 1 — View →
PSMB2 Proteasome subunit beta type-2 P49721 Cytoplasm 1 — View →
PSMB8 Proteasome subunit beta type-8 P28062 Cytoplasm 1 — View →
PSMB9 Proteasome subunit beta type-9 P28065 Cytoplasm 1 — View →
RARRES1 Retinoic acid receptor responder protein 1 P49788 Membrane 1 — View →
RBP4 Retinol-binding protein 4 P02753 Secreted 1 — View →
RET RET proto-oncogene O43519 — 1 — View →
RRM2 Ribonucleoside-diphosphate reductase subunit M2 P31350 Cytoplasm 1 — View →
RRM2B Ribonucleoside-diphosphate reductase subunit M2 B Q7LG56 Cytoplasm 1 — View →
SDC2 Syndecan-2 P34741 Membrane 1 — View →
SH2B3 SH2B adapter protein 3 Q9UQQ2 — 1 — View →
SIK1 Serine/threonine-protein kinase SIK1 P57059 Cytoplasm 1 — View →
SLC2A2 Solute carrier family 2, facilitated glucose transporter member 2 P11168 Membrane 1 — View →
STAT5B Signal transducer and activator of transcription 5B P51692 Cytoplasm 1 — View →
STMN4 Stathmin-4 Q9H169 Golgi apparatus 1 — View →
TF Serotransferrin P02787 Secreted 1 — View →
TNF Tumor necrosis factor P01375 Cell membrane 1 — View →
TNFRSF8 Tumor necrosis factor receptor superfamily member 8 P28908 Cell membrane 1 — View →
TNFSF11 Tumor necrosis factor ligand superfamily member 11 O14788 Cell membrane 1 — View →
TUBA1A Tubulin alpha-1A chain Q71U36 Cytoplasm 1 — View →
TUBB3 Tubulin beta-3 chain Q13509 Cytoplasm 1 — View →
TUBD1 Tubulin delta chain Q9UJT1 Cytoplasm 1 — View →
TUBE1 Tubulin epsilon chain Q9UJT0 Cytoplasm 1 — View →
TUBG1 Tubulin gamma-1 chain P23258 Cytoplasm 1 — View →
TXNRD1 Thioredoxin reductase 1, cytoplasmic Q16881 Cytoplasm 1 — View →
VEGFB Vascular endothelial growth factor B P49765 Secreted 1 — View →
YES1 Tyrosine-protein kinase Yes P07947 Cell membrane 1 — View →
ZAK Mitogen-activated protein kinase kinase kinase MLT Q9NYL2 Cytoplasm 1 — View →