FDA APPROVED ONCOLOGY DRUGS
Understanding
Drug Resistance
in Cancer Therapy
A curated database of resistance mutations, protein targets, and 3D structural data for FDA-approved oncology drugs.
169
Approved Drugs
232
Protein Targets
359+
Resistance Mutations
118
Drug–Target–PDB Triplets
Drug Archive
Browse all FDA-approved oncology drugs with mechanisms of action, approved indications, and known protein targets.
Browse Drugs →Protein Targets
Explore druggable oncology targets with UniProt annotations, co-crystal structures, and cross-drug resistance profiles.
Browse Targets →AI Assistant
Ask natural language questions about resistance mechanisms, specific mutations, or drug comparisons — grounded in COSMIC and PubMed data.
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