MPG

DNA-3-methyladenine glycosylase

P29372 ↗

1 Targeting Drugs

0 Resistance Mutations

1EWN Structure Loaded

3D Structure PDB: 1EWN

Switch structure: RCSB ↗

Protein Information

UniProt Accession P29372 ↗

Gene Name MPG

Cellular Location Cytoplasm

General Function Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

Targeting Drugs 1

Cisplatin Alkylating Agent

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