Mitotane
DB00648
Approved Indication
For treatment of inoperable adrenocortical tumours; Cushing's syndrome
5
Targets
0
Resistance Mutations
0
References
3D Structure
No structure available
No co-crystal structure available
Protein Targets
Mechanism of Action
Its biochemical mechanism of action is unknown, although data are available to suggest that the drug modifies the peripheral metabolism of steroids as well as directly suppressing the adrenal cortex.
Details
DrugBank ID
DB00648 ↗
Approval Date
2009-06-01
Molecular Weight
320.041 g/mol
Drug Class
Other
ATC Codes
L01XX23
Synonyms
Mitotan, Mitotane, Mitotano
PubChem
CID: 4211 ↗
ChEMBL
CHEMBL1670 ↗
SMILES
ClC(Cl)C(C1=CC=C(Cl)C=C1)C1=CC=CC=C1Cl
ADMET Profile
Computing properties…