Pipobroman
Alkylating Agent
DB00236
Approved Indication
For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
0
Targets
0
Resistance Mutations
0
References
3D Structure
No structure available
No co-crystal structure available
Protein Targets
Mechanism of Action
The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death.
Details
DrugBank ID
DB00236 ↗
Approval Date
—
Molecular Weight
356.054 g/mol
Drug Class
Alkylating Agent
ATC Codes
L01AX02
Synonyms
Vercyte
PubChem
CID: 4842 ↗
ChEMBL
CHEMBL1585 ↗
SMILES
BrCCC(=O)N1CCN(CC1)C(=O)CCBr
ADMET Profile
Computing properties…